Abbas S, Afzal S, Nadeem H, Hussain D, Langer P, Sévigny J, Ashraf Z, Iqbal J. Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors. Bioorganic chemistry. 2021-11-20. DOI: 10.1016/j.bioorg.2021.105456.
Abolghasemi A, Manca C, Iannotti FA, Shen M, Leblanc N, Lacroix S, Martin C, Flamand N, Di Marzo V, Silvestri C. Assessment of the Effects of Dietary Vitamin D Levels on Olanzapine-Induced Metabolic Side Effects: Focus on the Endocannabinoidome-Gut Microbiome Axis. Int J Mol Sci. 2021-11-28. DOI: 10.3390/ijms222212361.
Afzal S, Al-Rashida M, Hameed A, Pelletier J, Sévigny J, Iqbal J. Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase). Bioorganic chemistry. 2021-05-21. DOI: 10.1016/j.bioorg.2021.104957.
Allaeys I, Ribeiro de Vargas F, Bourgoin SG, Poubelle PE. Human Inflammatory Neutrophils Express Genes Encoding Peptidase Inhibitors: Production of Elafin Mediated by NF-κB and CCAAT/Enhancer-Binding Protein β. Journal of immunology. 2021-03-25. DOI: 10.4049/jimmunol.2000852.
Almeida-Brasil CC, Hanly JG, Urowitz M, Clarke AE, Ruiz-Irastorza G, Gordon C, Ramsey-Goldman R, Petri M, Ginzler EM, Wallace DJ, Bae SC, Romero-Diaz J, Dooley MA, Peschken C, Isenberg D, Rahman A, Manzi S, Jacobsen S, Lim S, van Vollenhoven RF, Nived O, Jönsen A, Kamen DL, Aranow C, Sanchez-Guerrero J, Gladman DD, Fortin PR, Alarcón GS, Merrill JT, Kalunian K, Ramos-Casals M, Steinsson K, Zoma A, Askanase A, Khamashta MA, Bruce IN, Inanc M, Abrahamowicz M, Bernatsky S. Flares after hydroxychloroquine reduction or discontinuation: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Annals of the rheumatic diseases. 2021-12-16. DOI: 10.1136/annrheumdis-2021-221295.
Andersen KM, Schieir O, Valois MF, Bartlett SJ, Bessette L, Boire G, Haraoui B, Hazlewood G, Hitchon C, Keystone EC, Pope J, Tin D, Throne JC, Bykerk VP, CATCH Investigators. A Bridge Too Far? Real-World Practice Patterns of Early Glucocorticoid Use in the Canadian Early Arthritis Cohort. ACR open rheumatology. 2021-10-28. DOI: 10.1002/acr2.11334.
Archambault AS, Tinto F, Dumais É, Rakotoarivelo V, Kostrzewa M, Plante PL, Martin C, Simard M, Silvestri C, Pouliot R, Laviolette M, Boulet LP, Vitale RM, Ligresti A, Di Marzo V, Flamand N. Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites - 13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils. Cells. 2021-09-28. DOI: 10.3390/cells10092322.
Archambault AS, Zaid Y, Rakotoarivelo V, Turcotte C, Dore E, Dubuc I, Martin C, Flamand O, Amar Y, Cheikh A, Fares H, El Hassani A, Tijani Y, Cote A, Laviolette M, Boilard E, Flamand L, Flamand N. High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients. FASEB journal: official publication of the Federation of American Societies for Experimental Biology. 2021-05-25, DOI: 10.1096/fj.202100540R.
Arif S, Attiogbe E, Moulin VJ. Granulation tissue myofibroblasts during normal and pathological skin healing: The interaction between their secretome and the microenvironment. Wound repair and regeneration: official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2021-04-22. DOI: 10.1111/wrr.12919.
Artusi S, Ruggiero E, Nadai M, Tosoni B, Perrone R, Ferino A, Zanin I, Xodo L, Flamand L, Richter SN. Antiviral Activity of the G-Quadruplex Ligand TMPyP4 against Herpes Simplex Virus-1. Viruses. 2021-02-02. DOI: 10.3390/v13020196.
Babou Kammoe RB, Kauffenstein G, Pelletier J, Robaye B, Sevigny J. NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female. Biomolecules. 2021-01-27. DOI: 10.3390/biom11020147.
Beaudoin C, Jean S, Moore L, Gamache P, Bessette L, Ste-Marie LG, Brown JP. Prediction of Osteoporotic Fractures in Elderly Individuals: A Derivation and Internal Validation Study Using Healthcare Administrative Data. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2021-09-07. DOI: 10.1002/jbmr.4438.
Berrazouane S, Doucet A, Boisvert M, Barabé F, Aoudjit F. VLA-4 Induces Chemoresistance of T Cell Acute Lymphoblastic Leukemia Cells via PYK2-Mediated Drug Efflux. Cancers. 2021-07-24. DOI: 10.3390/cancers13143512.
Boilard E, Machlus KR. Location is everything when it comes to megakaryocyte function. The Journal of clinical investigation. 2021-01-04. DOI :10.1172/JCI144964.
Bouzriba C, Chavez Alvarez AC, Gagné-Boulet M, Ouellette V, Lacroix J, Côté MF, C-Gaudreault R, Fortin S. Branched alkyl of phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as unique cytochrome P450 1A1-activated antimitotic prodrugs: Biological evaluation and mechanism of bioactivation. European journal of medicinal chemistry. 2021-11-29. DOI: 10.1016/j.ejmech.2021.114003.
Breton S, Battistone MA. Unexpected Participation of Intercalated Cells in Renal Inflammation and Acute Kidney Injury. Nephron. 2021-10-17. DOI: 10.1159/000519265.
Breton S, Kalavrouziotis D, Mohammadi S. Commentary: Novel preoperative predictors of acute kidney injury following cardiac surgery: Is it a game changer?. The Journal of thoracic and cardiovascular surgery. 2021-05-16. DOI: 10.1016/j.jtcvs.2021.04.055.
Caneparo C, Sorroza-Martinez L, Chabaud S, Fradette J, Bolduc S. Considerations for the clinical use of stem cells in genitourinary regenerative medicine. World journal of stem cells. 2021-11-17. DOI: 10.4252/wjsc.v13.i10.1480.
Chew C, Reynolds JA, Lertratanakul A, Wu P, Urowitz M, Gladman DD, Fortin PR, Bae SC, Gordon C, Clarke AE, Bernatsky S, Hanly JG, Isenberg D, Rahman A, Sanchez-Guerrero J, Romero-Diaz J, Merrill J, Wallace D, Ginzler E, Khamashta M, Nived O, Jönsen A, Steinsson K, Manzi S, Kalunian K, Dooley MA, Petri M, Aranow C, van Vollenhoven R, Stoll T, Alarcón GS, Lim SS, Ruiz-Irastorza G, Peschken CA, Askanase AD, Kamen DL, İnanç M, Ramsey-Goldman R, Bruce IN. Lower vitamin D is associated with metabolic syndrome and insulin resistance in systemic lupus: data from an international inception cohort. Rheumatology. 2021-02-08. DOI: 10.1093/rheumatology/keab090.
Dauchez A, Hankard A, Lacroix S. Interleukin-1 neuronal receptor induces pain in chronic inflammatory diseases. Medecine sciences. 2021-09-07 10. DOI: 1051/medsci/2021128.
de Azevedo Lopes E, Balbi GGM, Tektonidou MG, Pengo V, Sciascia S, Ugarte A, Belmont HM, Gerosa M, Fortin PR, Lopez-Pedrera C, Ji L, Cohen H, de Jesús GR, Branch DW, Nalli C, Petri M, Rodriguez E, Kello N, Ríos-Garcés R, Knight JS, Atsumi T, Willis R, Bertolaccini ML, Erkan D, Andrade D, APS ACTION. Clinical and laboratory characteristics of Brazilian versus non-Brazilian primary antiphospholipid syndrome patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) clinical database and repository. Advances in rheumatology. 2021-10-29. DOI: 10.1186/s42358-021-00222-3.
Depommier C, Flamand N, Pelicaen R, Maiter D, Thissen JP, Loumaye A, Hermans MP, Everard A, Delzenne NM, Di Marzo V, Cani PD. Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models. Cells. 2021-01-21. DOI: 10.3390/cells10010071.
Depommier C, Vitale RM, Iannotti FA, Silvestri C, Flamand N, Druart C, Everard A, Pelicaen R, Maiter D, Thissen JP, Loumaye A, Hermans MP, Delzenne NM, de Vos WM, Di Marzo V, Cani PD. Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists.Cells. 2021-01-23. DOI: 10.3390/cells10010185.
Dias AF, Scholl JN, Moritz CEJ, Kagami LP, das Neves GM, Eifler-Lima VL, Cruz-López O, Conejo-García A, Sévigny J, Battastini AMO, Campos JM, Figueiró F. New insights into cytotoxic mechanisms of bozepinib against glioblastoma. European journal of pharmaceutical sciences: official journal of the European Federation for Pharmaceutical Sciences. 2021-03-30. DOI: 10.1016/j.ejps.2021.105823.
Diaz C, Hayward CJ, Safoine M, Paquette C, Langevin J, Galarneau J, Théberge V, Ruel J, Archambault L, Fradette J. Ionizing radiation mediates dose dependant effects affecting the healing kinetics of wounds created on acute and late irradiated skin. Surgeries. 2021-01-28. DOI: 10.3390/surgeries2010004.
Dikranian A, Gold D, Bessette L, Nash P, Azevedo VF, Wang L, Woolcott J, Shapiro AB, Szumski A, Fleishaker D, Wollenhaupt J. Frequency and Duration of Early Non-serious Adverse Events in Patients with Rheumatoid Arthritis and Psoriatic Arthritis Treated with Tofacitinib. Rheumatology and therapy. 2021-12-18. DOI: 10.1007/s40744-021-00405-w.
Elkhalifa M, Orbai AM, Magder LS, Petri M, Alarcón GS, Gordon C, Merrill J, Fortin PR, Bruce IN, Isenberg D, Wallace D, Nived O, Ramsey-Goldman R, Bae SC, Hanly JG, Sanchez-Guerrero J, Clarke AE, Aranow C, Manzi S, Urowitz M, Gladman DD, Kalunian K, Werth VP, Zoma A, Bernatsky S, Khamashta M, Buyon JP, Dooley MA, Vollenhoven RV, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim S, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG, Jacobsen S. Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset. Lupus. 2021-05-07. DOI: 10.1177/09612033211014248.
Farlay D, Rizzo S, Ste-Marie LG, Michou L, Morin SN, Qiu S, Chavassieux P, Chapurlat RD, Rao SD, Brown JP, Boivin G. Duration-Dependent Increase of Human Bone Matrix Mineralization in Long-Term Bisphosphonate Users with Atypical Femur Fracture. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. 2021-01-12. DOI: 10.1002/jbmr.4244.
Gamara J, Davis L, Leong AZ, Pagé N, Rollet-Labelle E, Zhao C, Hongu T, Funakoshi Y, Kanaho Y, Aoudji F, Pelletier M, Bourgoin SG. Corrigendum to "Arf6 regulates energy metabolism in neutrophils" [Free Radic Biol Med. 172 (2021) 550-561]. Free radical biology & medicine. 2021-11-16. DOI: 10.1016/j.freeradbiomed.2021.11.013.
Gamara J, Davis L, Leong AZ, Pagé N, Rollet-Labelle E, Zhao C, Hongu T, Funakoshi Y, Kanaho Y, Aoudji F, Pelletier M, Bourgoin SG. Arf6 regulates energy metabolism in neutrophils. Free radical biology & medicine. 2021-07-10. DOI: 10.1016/j.freeradbiomed.2021.07.001.
Gravel A, Sanders W, Fournier E, Droit A, Moorman N, Flamand L. Mapping the Human Herpesvirus 6B transcriptome. Journal of virology. 2021-02-25. DOI: 10.1128/JVI.01335-20.
Grenier A, Legault J, Pichette A, Jean L, Bélanger A, Pouliot R. Antioxidant, Anti-Inflammatory, and Anti-Aging Potential of a Kalmia angustifolia Extract and Identification of Some Major Compounds. Antioxidants. 2021-08-28. DOI: 10.3390/antiox10091373.
Haas CB, Lovászi M, Pacher P, de Souza PO, Pelletier J, Leite RO, Sévigny J, Németh Z, Braganhol E, Haskó G. Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation. Purinergic signalling. 2021-10-04. DOI: 10.1007/s11302-021-09819-1.
Hanly JG, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin PR, Gladman DD, Urowitz MB, Bruce IN, Petri M, Ginzler EM, Dooley MA, Ramsey-Goldman R, Manzi S, Jonsen A, Alarcón GS, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Lim SS, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Farewell V. Neuropsychiatric Events in Systemic Lupus Erythematosus: Predictors of Occurrence and Resolution in a Longitudinal Analysis of an International Inception Cohort. Arthritis & rheumatology. 2021-05-27. DOI: 10.1002/art.41876.
Hasse S, Duchez AC, Fortin P, Boilard E, Bourgoin SG. Interplay between LPA2 and LPA3 in LPA-mediated phosphatidylserine cell surface exposure and extracellular vesicles release by erythrocytes. Biochemical pharmacology. 2021-07-03. DOI: 10.1016/j.bcp.2021.114667.
Hoa S, Bernatsky S, Baron M, Proudman S, Stevens W, Sahhar J, Wang M, Steele RJ, Canadian Scleroderma Research Group (CSRG), Australian Scleroderma Interest Group (ASIG), Nikpour M, Hudson M. Association Between Immunosuppressive Therapy and Incident Risk of Interstitial Lung Disease in Systemic Sclerosis. Chest. 2021-06-21. DOI: 10.1016/j.chest.2021.06.014.
Iqbal J, Jacob C, Sévigny J. Editorial: Metalloenzymes: Potential Drug Targets Frontiers in pharmacology. 2021-10-11. DOI: 10.3389/fphar.2021.746925.
Johnson SR, Gladman DD, Brunner HI, Isenberg D, Clarke AE, Barber MRW, Arnaud L, Fortin PR, Mosca M, Voskuyl A, Manzi S, Aranow C, Askanase A, Alarcón GS, Bae SC, Costedoat-Chalumeau N, English J, Pons-Estel GJ, Pons-Estel BA, Gilman R, Ginzler E, Hanly JG, Jacobsen S, Kalunian K, Kamen DL, Lambalgen C, Legge A, Lim SS, Mak A, Morand EF, Peschken C, Petri M, Rahman A, Ramsey-Goldman R, Reynolds JA, Romero-Diaz J, Ruiz-Irastorza G, Sanchez-Guerrero J, Svenungsson E, Touma Z, Urowitz M, Vinet E, van Vollenhoven RF, Waldhauser H, Wallace D, Zoma A, Bruce IN. Evaluating the construct of damage in systemic lupus erythematosus. Arthritis care & research. 2021-12-28. DOI: 10.1002/acr.24849.
Kawecki F, Galbraith T, Clafshenkel WP, Fortin M, Auger FA, Fradette J. In Vitro Prevascularization of Self-Assembled Human Bone-Like Tissues and Preclinical Assessment Using a Rat Calvarial Bone Defect Model. Materials. 2021-04-30. DOI: 10.3390/ma14082023.
Kelly C, Wallace D, Moulin V, Germain L, Zuccaro J, Galdyn I, Fish JS. Surviving an Extensive Burn Injury Using Advanced Skin Replacement Technologies. Journal of burn care & research: official publication of the American Burn Association. 2021-08-03. DOI: 10.1093/jbcr/irab146.
Khaddaj-Mallat R, Aldib N, Bernard M, Paquette AS, Ferreira A, Lecordier S, Saghatelyan A, Flamand L, ElAli A. SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein. Neurobiology of disease. 2021-11-15. DOI: 10.1016/j.nbd.2021.105561.
Kothari C, Clemenceau A, Ouellette G, Ennour-Idrissi K, Michaud A, C-Gaudreault R, Diorio C, Durocher F. TBC1D9: An Important Modulator of Tumorigenesis in Breast Cancer. Cancers. 2021-07-24. DOI: 10.3390/cancers13143557.
Lacouture A, Jobin C, Weidmann C, Berthiaume L, Bastien D, Laverdière I, Pelletier M, Audet-Walsh É. A FACS-Free Purification Method to Study Estrogen Signaling, Organoid Formation, and Metabolic Reprogramming in Mammary Epithelial Cells Frontiers in endocrinology. 2021-08-30. DOI: 10.3389/fendo.2021.672466.
Lacouture A, Lafront C, Peillex C, Pelletier M, Audet-Walsh É. Impacts of endocrine-disrupting chemicals on prostate function and cancer. Environmental research. 2021-09-25. DOI: 10.1016/j.envres.2021.112085.
Lamontagne-Proulx J, Coulombe K, Dahhani F, Côté M, Guyaz C, Tremblay C, Di Marzo V, Flamand N, Calon F, Soulet D. Effect of Docosahexaenoic Acid (DHA) at the Enteric Level in a Synucleinopathy Mouse Model. Nutrients. 2021-12-29. DOI: 10.3390/nu13124218.
Lee YC, Fox RS, Kwakkenbos L, Levis B, Carrier ME, Welling J, Sauvé M, Mouthon L, Benedetti A, Bartlett SJ, Varga J, Thombs BD, Scleroderma Patient-centered Intervention Network Investigators. Pain levels and associated factors in the Scleroderma Patient-centered Intervention Network (SPIN) cohort: a multicentre cross-sectional study. Rheumatology. 2021-12-01. DOI: 10.1016/S2665-9913(21)00318-0.
Lopes DV, de Fraga Dias A, Silva LFL, Scholl JN, Sévigny J, Battastini AMO, Figueiró F. Influence of NSAIDs and methotrexate on CD73 expression and glioma cell growth. Purinergic signalling. 2021-03-21. DOI: 10.1007/s11302-021-09775-w.
Lopez V, Schakel L, Schuh HJM, Schmidt MS, Mirza S, Renn C, Pelletier J, Lee SY, Sevigny J, Alban S, Bendas G, Muller CE. Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39. Marine drugs. 2021-01-27. DOI: 10.3390/md19020051.
Mai L, Asaduzzaman A, Noamani B, Fortin PR, Gladman DD, Touma Z, Urowitz MB, Wither J. The baseline interferon signature predicts disease severity over the subsequent 5 years in systemic lupus erythematosus. Arthritis research & therapy. 2021-01-16. DOI: 10.1186/s13075-021-02414-0.
Manca C, Lacroix S, Pérusse F, Flamand N, Chagnon Y, Drapeau V, Tremblay A, Di Marzo V, Silvestri C. Oral Capsaicinoid Administration Alters the Plasma Endocannabinoidome and Fecal Microbiota of Reproductive-Aged Women Living with Overweight and Obesity. Biomedicines. 2021-09-29. DOI: 10.3390/biomedicines9091246.
Manojlovic-Stojanoski M, Lavrnja I, Stevanovic I, Trifunovic S, Ristic N, Nestorovic N, Sevigny J, Nedeljkovic N, Laketa D. Antenatal Dexamethasone Treatment Induces Sex-dependent Upregulation of NTPDase1/CD39 and Ecto-5'-nucleotidase/CD73 in the Rat Fetal Brain. Cellular and molecular neurobiology. 2021-03-24. DOI: 10.1007/s10571-021-01081-8.
Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Florea BI, Dieude M, Vingert B, Boilard E, Overkleeft HS. Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules. Blood. 2021-07-22. DOI: 10.1182/blood.2020009957.
Mariani M, Zimmerman C, Rodriguez P, Hasenohr E, Aimola G, Gerrard DL, Richman A, Dest A, Flamand L, Kaufer B, Frietze S. Higher-Order Chromatin Structures of Chromosomally Integrated HHV-6A Predict Integration Sites. Frontiers in cellular and infection microbiology. 2021-03-15. DOI: 10.3389/fcimb.2021.612656.
Mazilescu LI, Urbanellis P, Kaths MJ, Ganesh S, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli DJ, Turgeon J, Karakeusian Rimbaud A, Hébert MJ, Dieudé M, Alleys I, Dore E, Boilard E, Overkleeft HS, Willems LI, Robinson LA, Selzner M. Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts. Transplantation direct. 2021-09-13. DOI: 10.1097/TXD.0000000000001218.
Melki I, Allaeys I, Tessandier N, Levesque T, Cloutier N, Laroche A, Vernoux N, Becker Y, Benk-Fortin H, Zufferey A, Rollet-Labelle E, Pouliot M, Poirier G, Patey N, Belleannee C, Soulet D, McKenzie SE, Brisson A, Tremblay ME, Lood C, Fortin PR, Boilard E. Platelets release mitochondrial antigens in systemic lupus erythematosus. Science translational medicine. 2021-02-18. DOI: 10.1126/scitranslmed.aav5928.
Michou L, Julien AS, Witteman HO, Légaré J, Ratelle L, Godbout A, Tardif J, Côté S, Boily G, Lui R, Ikic A, Trudeau H, Tremblay JL, Fortin I, Bessette L, Chetaille AL, Fortin PR. Measuring the impact of an educational intervention in rheumatoid arthritis: An open-label, randomized trial. Archives of rheumatology. 2021-12-24. DOI: 10.46497/ArchRheumatol.2022.8965.
Morin S, Simard M, Flamand N, Pouliot R. Biological action of docosahexaenoic acid in a 3D tissue-engineered psoriatic skin model: Focus on the PPAR signaling pathway. Biochim. Biophys. Acta - Mol. Cell Biol. Lipids. 2021-08-24. DOI: 10.1016/j.bbalip.2021.159032.
Moulin VJ. Three-Dimensional Model of Hypertrophic Scar Using a Tissue-Engineering Approach. Methods in molecular biology. 2021-05-24. DOI: 10.1007/978-1-0716-1382-5_28.
Murtaza A, Afzal S, Zaman G, Saeed A, Pelletier J, Sévigny J, Iqbal J, Hassan A. Divergent synthesis and elaboration of structure activity relationship for quinoline derivatives as highly selective NTPDase inhibitor. Bioorganic chemistry. 2021-08-20. DOI: 10.1016/j.bioorg.2021.105240.
Paré G, Vitry J, Merchant ML, Vaillancourt M, Murru A, Shen Y, Elowe S, Lahoud MH, Naccache PH, McLeish KR, Fernandes MJ. The Inhibitory Receptor CLEC12A Regulates PI3K-Akt Signaling to Inhibit Neutrophil Activation and Cytokine Release. Frontiers in immunology. 2021-07-08. DOI: 10.3389/fimmu.2021.650808.
Pellerin È, Chabaud S, Pouliot F, Pelletier M, Bolduc S. Bisphenol A Alters the Energy Metabolism of Stromal Cells and Could Promote Bladder Cancer Progression. Cancers. 2021-11-13. DOI: 10.3390/cancers13215461.
Pellerin FA, Caneparo C, Pellerin È, Chabaud S, Pelletier M, Bolduc S. Heat-Inactivation of Fetal and Newborn Sera Did Not Impair the Expansion and Scaffold Engineering Potentials of Fibroblasts. Bioengineering. 2021-11-25. DOI: 10.3390/bioengineering8110184.
Poluri RTK, Paquette V, Allain ÉP, Lafront C, Joly-Beauparlant C, Weidmann C, Droit A, Guillemette C, Pelletier M, Audet-Walsh É. KLF5 and NFYA factors as novel regulators of prostate cancer cell metabolism. Endocrine-related cancer. 2021-03-10. DOI: 10.1530/ERC-20-0504.
Puhm F, Flamand L, Boilard E. Platelet extracellular vesicles in COVID-19: Potential markers and makers. Journal of leukocyte biology. 2021-11-03. DOI: 10.1002/JLB.3MIR0221-100R.
Rakotoarivelo V, Sihag J, Flamand N. Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism. Cells. 2021-06-03. DOI: 10.3390/cells10061279.
Rioux G, Simard M, Morin S, Lorthois I, Guérin SL, Pouliot R. Development of a 3D psoriatic skin model optimized for infiltration of IL-17A producing T cells: Focus on the crosstalk between T cells and psoriatic keratinocytes. Acta biomaterialia. 2021-09-21. DOI: 10.1016/j.actbio.2021.09.018.
Rodriguez-Martinez A, Trapero C, Vidal A, Piulats JM, Gomez de Aranda I, Sevigny J, Fernandez-Montoli ME, Ponce J, Matias-Guiu X, Martin-Satue M. Characterization of the Endometrial MSC Marker Ectonucleoside Triphosphate Diphosphohydrolase-2 (NTPDase2/CD39L1) in Low- and High-Grade Endometrial Carcinomas: Loss of Stromal Expression in the Invasive Phenotypes. Journal of personalized medicine. 2021-04-30. DOI: 10.3390/jpm11050331.
Rubenich DS, de Souza PO, Omizzollo N, Lenz GS, Sevigny J, Braganhol E. Neutrophils: fast and furious-the nucleotide pathway. Purinergic signalling. 2021-04-29. DOI : 10.1007/s11302-021-09786-7.
Ruel-Gagné S, Simonyan D, Légaré J, Bessette L, Fortin PR, Lacaille D, Dogba MJ, Michou L. Expectations and educational needs of rheumatologists, rheumatology fellows and patients in the field of precision medicine in Canada, a quantitative cross-sectional and descriptive study. BMC rheumatology. 2021-11-29. DOI: 10.1186/s41927-021-00222-2.
Saba I, Barat C, Chabaud S, Reyjon N, Leclerc M, Jakubowska W, Orabi H, Lachhab A, Pelletier M, Tremblay MJ, Bolduc S. Immunocompetent Human 3D Organ-Specific Hormone-Responding Vaginal Mucosa Model of HIV-1 Infection. Tissue engineering. 2021-02-12. DOI: 10.1089/ten.TEC.2020.0333.
Salem M, Lecka J, Pelletier J, Gomes Marconato D, Dumas A, Vallières L, Brochu G, Robaye B, Jobin C, Sévigny J. NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD. Gut. 2021-01-16. DOI: 10.1136/gutjnl-2020-320937.
Sandhu B, Tran S, Singhal G, Syed I, Feldbrügge L, Mitsuhashi S, Pelletier J, Huang J, Yalcin Y, Csizmadia E, Tiwari-Heckler S, Enjyoji K, Sévigny J, Maratos-Flier E, Robson SC, Jiang ZG, Perez-Matos MC. Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism. Metabolism. 2021-02-25. DOI: 10.1016/j.metabol.2021.154731.
Schachter J, Alvarez CL, Bazzi Z, Faillace MP, Corradi G, Hattab C, Rinaldi DE, Gonzalez-Lebrero R, Molineris MP, Sévigny J, Ostuni MA, Schwarzbaum PJ. Extracellular ATP hydrolysis in Caco-2 human intestinal cell line. Biochim Biophys Acta Biomembr. 2021-07-03. DOI: 10.1016/j.bbamem.2021.183679.
Schäkel L, Mirza S, Pietsch M, Lee SY, Keuler T, Sylvester K, Pelletier J, Sévigny J, Pillaiyar T, Namasivayam V, Gütschow M, Müller CE. 2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. Archiv der Pharmazie. 2021-10-26. DOI: 10.1002/ardp.202100300.
Simard M, Rioux G, Morin S, Martin C, Guérin SL, Flamand N, Julien P, Fradette J, Pouliot R. Investigation of Omega-3 Polyunsaturated Fatty Acid Biological Activity in a Tissue-Engineered Skin Model Involving Psoriatic Cells. The Journal of investigative dermatology. 2021-04-15. DOI: 10.1016/j.jid.2021.02.755.
Simard M, Tremblay A, Morin S, Martin C, Julien P, Fradette J, Flamand N, Pouliot R. α-Linolenic acid and linoleic acid modulate the lipidome and the skin barrier of a tissue-engineered skin model. Acta biomaterialia. 2021-11-22. DOI: 10.1016/j.actbio.2021.11.021.
Suriano F, Manca C, Flamand N, Depommier C, Van Hul M, Delzenne NM, Silvestri C, Cani PD, Di Marzo V. Exploring the endocannabinoidome in genetically obese (ob/ob) and diabetic (db/db) mice: Links with inflammation and gut microbiota. Biochim Biophys Acta Mol Cell Biol Lipids. 2021-10-05. DOI: 10.1016/j.bbalip.2021.159056.
Tardif JC, Bouabdallaoui N, L'Allier PL, Gaudet D, Shah B, Pillinger MH, Lopez-Sendon J, da Luz P, Verret L, Audet S, Dupuis J, Denault A, Pelletier M, Tessier PA, Samson S, Fortin D, Tardif JD, Busseuil D, Goulet E, Lacoste C, Dubois A, Joshi AY, Waters DD, Hsue P, Lepor NE, Lesage F, Sainturet N, Roy-Clavel E, Bassevitch Z, Orfanos A, Stamatescu G, Grégoire JC, Busque L, Lavallée C, Hétu PO, Paquette JS, Deftereos SG, Levesque S, Cossette M, Nozza A, Chabot-Blanchet M, Dubé MP, Guertin MC, Boivin G, COLCORONA Investigators. Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial. Respiratory medicine. 2021-05-30. DOI: 10.1016/S2213-2600(21)00222-8.
Thérien A, Cieślak A, Verreault M, Perreault M, Trottier J, Gobeil S, Vohl MC, Barbier O. Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid. Nutrients. 2021-08-27. DOI: 10.3390/nu13082617.
Tinto F, Archambault AS, Dumais É, Rakotoarivelo V, Kostrzewa M, Martin C, Plante PL, Desjardins Y, Simard M, Pouliot R, De Petrocellis L, Ligresti A, Di Marzo V, Flamand N. Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva. Biochim Biophys Acta Mol Cell Biol Lipids. 2021-04-29. DOI: 10.1016/j.bbalip.2021.158954.
Tourzani DA, Battistone MA, Salicioni AM, Breton S, Visconti PE, Gervasi MG. Caput Ligation Renders Immature Mouse Sperm Motile and Capable to Undergo cAMP-Dependent Phosphorylation. International journal of molecular sciences. 2021-10-13. DOI: 10.3390/ijms221910241.
Tremblay A, Simard M, Morin S, Pouliot R. Docosahexaenoic Acid Modulates Paracellular Absorption of Testosterone and Claudin-1 Expression in a Tissue-Engineered Skin Model. International journal of molecular sciences. 2021-12-10 . DOI: 10.3390/ijms222313091.
Ugarte-Gil MF, Mak A, Leong J, Dharmadhikari B, Kow NY, Reátegui-Sokolova C, Elera-Fitzcarrald C, Aranow C, Arnaud L, Askanase AD, Bae SC, Bernatsky S, Bruce IN, Buyon J, Costedoat-Chalumeau N, Dooley MA, Fortin PR, Ginzler EM, Gladman DD, Hanly J, Inanc M, Isenberg D, Jacobsen S, James JA, Jönsen A, Kalunian K, Kamen DL, Lim SS, Morand E, Mosca M, Peschken C, Pons-Estel BA, Rahman A, Ramsey-Goldman R, Reynolds J, Romero-Diaz J, Ruiz-Irastorza G, Sánchez-Guerrero J, Svenungsson E, Urowitz M, Vinet E, van Vollenhoven RF, Voskuyl A, Wallace DJ, Petri MA, Manzi S, Clarke AE, Cheung M, Farewell V, Alarcon GS. Impact of glucocorticoids on the incidence of lupus-related major organ damage: a systematic literature review and meta-regression analysis of longitudinal observational studies. Lupus science & medicine. 2021-12-21. DOI: 10.1136/lupus-2021-000590.
Ullah S, El-Gamal MI, El-Gamal R, Pelletier J, Sevigny J, Shehata MK, Anbar HS, Iqbal J. Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents. European journal of medicinal chemistry. 2021-03-21. DOI: 10.1016/j.ejmech.2021.113339.
Vaillancourt M, Desaulniers P, Paré G, Pagé N, Lachhab A, Kerever A, Julien AS, Amiable N, Pelletier M, Tessier PA, Bessette L, Michou L, Fortin PR, Fernandes MJ. Expression of the myeloid inhibitory receptor CLEC12A correlates with disease activity and cytokines in early rheumatoid arthritis. Scientific reports. 2021-05-28. DOI: 10.1038/s41598-021-90631-7.
Vaillancourt M, Hubert A, Subra C, Boucher J, Bazie WW, Vitry J, Berrazouane S, Routy JP, Trottier S, Tremblay C, Jenabian MA, Benmoussa A, Provost P, Tessier PA, Gilbert C. Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA. Pathogens. 2021-04-30. DOI: 10.3390/pathogens10050526.
Vézina-Dawod S, Perreault M, Guay LD, Gerber N, Gobeil S, Biron E. Synthesis and biological evaluation of novel 1,4-benzodiazepin-3-one derivatives as potential antitumor agents against prostate cancer . Bioorganic & medicinal chemistry. 2021-08-01. DOI: 10.1016/j.bmc.2021.116314.
Villot R, Poirier A, Bakan I, Boulay K, Fernández E, Devillers R, Gama-Braga L, Tribouillard L, Gagné A, Duchesne É, Caron D, Bérubé JS, Bérubé JC, Coulombe Y, Orain M, Gélinas Y, Gobeil S, Bossé Y, Masson JY, Elowe S, Bilodeau S, Manem V, Joubert P, Mallette FA, Laplante M. ZNF768 links oncogenic RAS to cellular senescence. Nature communications. 2021-08-18. DOI: 10.1038/s41467-021-24932-w.
Vitry J, Paré G, Murru A, Charest-Morin X, Maaroufi H, McLeish KR, Naccache PH, Fernandes MJ. Regulation of the Expression, Oligomerisation and Signaling of the Inhibitory Receptor CLEC12A by Cysteine Residues in the Stalk Region. International journal of molecular sciences. 2021-10-13. DOI: 10.3390/ijms221910207.
Wood ML, Veal CD, Neumann R, Suárez NM, Nichols J, Parker AJ, Martin D, Romaine SP, Codd V, Samani NJ, Voors AA, Tomaszewski M, Flamand L, Davison AJ, Royle NJ. Variation in human herpesvirus 6B telomeric integration, excision, and transmission between tissues and individuals. eLife. 2021-09-21. DOI: 10.7554/eLife.70452.
Zaid Y, Doré É, Dubuc I, Archambault AS, Flamand O, Laviolette M, Flamand N, Boilard É, Flamand L. Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19. The Journal of allergy and clinical immunology. 2021-06-10. DOI: 10.1016/j.jaci.2021.05.032.
Zaid Y, Guessous F, Puhm F, Elhamdani W, Chentoufi L, Morris AC, Cheikh A, Jalali F, Boilard E, Flamand L. Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19. Blood advances. 2021-02-09. DOI: 10.1182/bloodadvances.2020003513
Zhao Y, Hasse S, Bourgoin SG. Phosphatidylserine-specific phospholipase A1: A friend or the devil in disguise. Progress in lipid research. 2021-06-24. DOI: 10.1016/j.plipres.2021.101112.
Zhao Y, Hasse S, Vaillancourt M, Zhao C, Davis L, Boilard E, Fortin P, Di Battista J, Poubelle PE, Bourgoin SG. Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis. International journal of molecular sciences. 2021-12-10. DOI: 10.3390/ijms222312685.